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Displaying Tag 'Genome'
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An international consortium of more than 68 scientists plan to create a “zoo of the genome, a collection of DNA sequences from 10,000 species of vertebrates, almost one for each kind of vertebrate. Is 10K Genome Project which will constitute the most comprehensive study of animal evolution ever attempted.
 10K Genome Project will collect samples of thousands of animals from zoos, museums and university collections around the world and then sequenced the genome of each species to reveal its complete genetic inheritance. The group of 68 scientists and common denominators of genome scientists 10K (G10KCOS) project began in April 2009 at a meeting at the University of California (UC), Santa Cruz (USA).
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Researchers at the Salk Institute in California (USA) have developed the first detailed map of the human epigenome, ie the set of modifications of the genome involved in pathologies like cancer, Alzheimer’s and various mental illnesses.
Although the human genome sequence detailing each DNA base of nearly 3,000 million bases that make up the human genome itself does not explain how it regulates its function.
“Before, we simply seeing anecdotal evidence of the epigenome,” says Joseph Ecker, author of the study and director of the Genomic Analysis Laboratory at the Salk Institute.
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Two new loci of susceptibility to multiple sclerosis (MS) have been identified by the Australia and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene). The researchers conducted an association study on the entire genome (gwas for Genome-wide association studies) to compare the genomes of 1618 patients and 3413 healthy people.
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The acute forms of cancer are often related to the overexpression of genes that promote cancer (oncogenes). Researchers at the Genome Institute of Singapore (GIS) and the Agency for Science, Technology and Research (A * STAR) have recently identified a gene (or RAB11FIP1 RCP) that is frequently amplified and overexpressed in breast cancer, it contributes functionally with aggressive breast cancers.
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